ABSTRACT. The increasing adoption of multi-cloud architectures has transformed how organizations manage digital operations, offering greater resilience, performance optimization, and cost efficiency. Yet, the diversity of global privacy laws continues to complicate compliance efforts. Regulations such as the General Data Protection Regulation (GDPR), the California Consumer Privacy Act (CCPA), and China’s Personal Information Protection Law (PIPL) differ not only in their principles but also in the mechanisms they prescribe for data handling, storage, and transfer across borders. This paper investigates the challenges of maintaining privacy compliance within multi-cloud environments that operate across multiple jurisdictions. Through a combined analysis of real-world case studies and compliance evaluation techniques, the study identifies recurring gaps such as inconsistent data residency policies, weak contractual safeguards, and fragmented auditing practices. In response, a comprehensive compliance framework is proposed one that integrates regulatory mapping, risk-based control mechanisms, and automated compliance monitoring to enable consistent adherence across cloud platforms. Empirical observations indicate that the adoption of this framework can substantially reduce regulatory exposure, improve enterprise data governance, and foster trustworthy, compliant cloud operations. Overall, the study contributes a practical approach for enterprises seeking to align technological innovation with the evolving global landscape of privacy and data protection.